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1

Total Synthesis of Indole and Dihydroindole Alkaloids. IX Studies on the synthesis of bisindole alkaloids in the vinblastine- vincristine series. The biogenetic approach

James P. Kutney, Toshihiko Hibino, Edwin Jahngen, Tetsuya Okutani, Arnold H. Ratcliffe, Adi M. Treasurywala, Stephen Wunderly

Journal:

Helvetica Chimica Acta

Year:

1976

Language:

english

File:

PDF, 1.55 MB

english, 1976

2

CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14. [Erratum to document cited in CA116(15):143280r]

Diana, Guy D., Kowalczyk, Paul, Treasurywala, Adi M., Oglesby, Richard C., Pevear, Daniel C., Dutko, Frank J.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 54 KB

english, 1992

3

Application of Genetic Algorithms to Combinatorial Synthesis: A Computational Approach to Lead Identification and Lead Optimization †,∇

Singh, Jasbir, Ator, Mark A., Jaeger, Edward P., Allen, Martin P., Whipple, David A., Soloweij, James E., Chowdhary, Swapan, Treasurywala, Adi M.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 450 KB

english, 1996

4

Migration arrest in glioma cells is dependent on the αv integrin subunit

Sherri Treasurywala, Michael E. Berens

Journal:

Year:

1998

Language:

english

File:

PDF, 170 KB

english, 1998

5

Docking flexible molecules: A case study of three proteins

R. S. Judson, Y. T. Tan, E. Mori, C. Melius, E. P. Jaeger, A. M. Treasurywala, A. Mathiowetz

Journal:

Journal of Computational Chemistry

Year:

1995

Language:

english

File:

PDF, 1.31 MB

english, 1995

6

Conformational searching methods for small molecules. I. Study of the sybyl search method

A.K. Ghose, E.P. Jaeger, P.J. Kowalczyk, M.L. Peterson, A.M. Treasurywala

Journal:

Journal of Computational Chemistry

Year:

1993

Language:

english

File:

PDF, 1.42 MB

english, 1993

7

Conformational energy downward driver (CEDD): Characterization and calibration of the method

E. P. Jaeger, M. L. Peterson, A. M. Treasurywala

Journal:

Journal of Computer-Aided Molecular Design

Year:

1995

Language:

english

File:

PDF, 804 KB

english, 1995

8

Enantiomeric effects of homologs of disoxaril on the inhibitory activity against human rhinovirus-14

Diana, Guy D., Otto, Michael J., Treasurywala, Adi M., McKinlay, Mark A., Oglesby, Richard C., Maliski, Edward G., Rossmann, Michael G., Smith, Thomas J.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 2.04 MB

english, 1988

9

Are Oxazolidinones Really Unproductive, Parasitic Species in Proline Catalysis? – Thoughts and Experiments Pointing to an Alternative View

Dieter Seebach, Albert K. Beck, D. Michael Badine, Michael Limbach, Albert Eschenmoser, Adi M. Treasurywala, Reinhard Hobi, Walter Prikoszovich, Bernard Linder

Journal:

Helvetica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 1.62 MB

english, 2007

10

Interferon-β inhibits proliferation and progression through S phase of the cell cycle in five glioma cell lines

Judith I. Garrison, Michael E. Berens, Joan Rankin Shapiro, Sherri Treasurywala, Georgia Floyd-Smith

Journal:

Journal of Neuro-Oncology

Year:

1996

Language:

english

File:

PDF, 788 KB

english, 1996

11

6-(4-Pyridinyl)-1H-1,2,3-triazolo[4,5-d]-pyrimidin-4(5H)-one: A Structurally Novel Competitive AMPA Receptor Antagonist

Subramanyam, Chakrapani, Ault, Brian, Sawutz, David, Bacon, Edward R., Singh, Baldev, Pennock, Patrick O., Kelly, Michael D., Kraynak, Matthew, Krafte, Doug, Treasurywala, Adi

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 290 KB

english, 1995

12

N-[[5-(Trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]-N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor

Sestanj, Kazimir, Bellini, Francesco, Fung, Steven, Abraham, Nedumparambil, Treasurywala, Adi, Humber, Leslie, Simard-Dequesne, Nicole, Dvornik, Dushan

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 270 KB

english, 1984

13

Enzyme Immunoassay of Testosterone, 17β-Estradiol, and Progesterone in Perspiration and Urine of Preadolescents and Young Adults: Exceptional Levels in Men's Axillary Perspiration

Muir, C., Treasurywala, K., McAllister, S., Sutherland, J., Dukas, L., Berger, R., Khan, A., deCatanzaro, D.

Journal:

Hormone and Metabolic Research

Year:

2008

Language:

english

File:

PDF, 228 KB

english, 2008

14

A few critical aspects of molecular superimposition of flexible organic molecules

ArupK. Ghose, AdiM. Treasurywala, MargaretE. Logan, Roben Wahl, Bruce Tomczuk, Rahm Goswami, EdwardP. Jaeger

Journal:

Journal of Molecular Graphics

Year:

1993

Language:

english

File:

PDF, 133 KB

english, 1993

15

Computer assisted design and synthesis of novel aldose reductase inhibitors

Butera, John, Bagli, Jehan, Doubleday, Wendel, Humber, Leslie, Treasurywala, Adi, Loughney, Deborah, Sestanj, Kazimir, Millen, Jane, Sredy, Janet

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 3.76 MB

english, 1989

16

A theoretical investigation of the N-oxide moiety

Robert B. Perni, Paul J. Kowalczyk, Adi M. Treasurywala, Michael Tracy

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 197 KB

english, 1995

17

Structure and absolute configuration of (+)-coronaridine hydrobromide. Absolute configuration of the Iboga alkaloids

Kutney, J. P., Fuji, Kaoru., Treasurywala, Adi M., Fayos, Jose., Clardy, Jon., Scott, A. Ian., Wei, C. C.

Journal:

Journal of the American Chemical Society

Year:

1973

Language:

english

File:

PDF, 387 KB

english, 1973

18

ChemInform Abstract: Ligand-Receptor Interactions via Hydrogen-Bond Formation. Synthesis and Pharmacological Evaluation of Pyrrolo and Pyrido Analogues of the Cardiotonic Agent 7-Hydroxycyclindole.

DIONNE, G., HUMBER, L. G., ASSELIN, A., MCQUILLAN, J., TREASURYWALA, A. M.

Journal:

Year:

1987

File:

PDF, 231 KB

1987

19

ChemInform Abstract: STRUCTURE AND ABSOLUTE CONFIGURATION OF (+)-CORONARIDINE HYDROBROMIDE, A COMMENT ON THE ABSOLUTE CONFIGURATION OF THE IBOGA ALKALOIDS

KUTNEY, J. P., FUJI, KAORU, TREASURYWALA, ADI M., FAYOS, JOSE, CLARDY, JON, SCOTT, A. IAN, WEI, C. C.

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 78 KB

1973

20

ChemInform Abstract: STUDIES ON THE SYNTHESIS OF BISINDOLE ALKALOIDS. THE SYNTHESIS, STRUCTURE AND ABSOLUTE CONFIGURATION OF 18′-EPI-4′-DEOXO-EPIVINBLASTINE, 18′-DECARBOMETHOXY-18′-EPI-4′-EPIVINBLASTINE AND 18′-EPI-3′,4′-DEHYDROVINBLASTINE

KUTNEY, J. P., COOK, J., FUJI, K., TREASURYWALA, A. M., CLARDY, J., FAYOS, J., WRIGHT, C.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 106 KB

1975

21

Computer-assisted investigation of structure-activity relationships in serotonin-uptake blockers

L G Humber, D Lee, S Rakhit, A M Treasurywala

Journal:

Journal of Molecular Graphics

Year:

1985

Language:

english

File:

PDF, 750 KB

english, 1985

22

Novel Inhibitors of the Nuclear Factor of Activated T Cells (NFAT)-Mediated Transcription of .beta.-Galactosidase: Potential Immunosuppressive and Antiinflammatory Agents

Michne, William F., Schroeder, Joseph D., Guiles, Joseph W., Treasurywala, Adi M., Weigelt, Carolyn A., Stansberry, Mary F., McAvoy, Elizabeth, Shah, Chandra R., Bump, Elizabeth

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.53 MB

english, 1995

23

Ligand-receptor interactions via hydrogen-bond formation. Synthesis and pharmacological evaluation of pyrrolo and pyrido analogs of the cardiotonic agent 7-hydroxycyclindole

Dionne, Gervais, Humber, Leslie G., Asselin, Andre, McQuillan, Juanita, Treasurywala, Adi M.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 864 KB

english, 1986

24

Studies on the Synthesis of Bisindole Alkaloids. II. The Synthesis of 3’,4’-Dehydrovinblastine, 4’-Deoxovinblastine and Related Analogues. The Biogenetic Approach

Peter Kutney, James, H. Ratcliffe, Arnold, M. Treasurywala, Adi, Wunderly, Stephen

Journal:

Year:

1975

Language:

english

File:

PDF, 174 KB

english, 1975

25

A comparison of a direct search method and a genetic algorithm for conformational searching

Meza, J. C., Judson, R. S., Faulkner, T. R., Treasurywala, A. M.

Journal:

Journal of Computational Chemistry

Year:

1996

Language:

english

File:

PDF, 780 KB

english, 1996

26

A genetic algorithm based method for docking flexible molecules

R.S. Judson, E.P. Jaeger, A.M. Treasurywala

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

1994

Language:

english

File:

PDF, 1.47 MB

english, 1994

27

Studies on the Synthesis of Bisindole Alkaloids. The Synthesis, Structure and Absolute Configuration of 18’-Epi-4’-deoxo-4’-epivinblastine, 18’-Decarbomethoxy-18’-epi-4’-epivinblastine and 18’-Epi-3’,4’-dehydrovinblastine

Peter Kutney, James, Cook, James, Fuji, Kaoru, M. Treasurywala, Adi, Clardy, Jon, Fayos, Jose, Wright, Hal

Journal:

Year:

1975

Language:

english

File:

PDF, 132 KB

english, 1975

28

CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14

Diana, Guy D., Kowalczyk, Paul, Treasurywala, Adi M., Oglesby, Richard C., Pevear, Daniel C., Dutko, Frank J.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 3.93 MB

english, 1992

29

Conformational searching methods for small molecules. III. Study of stochastic methods available in SYBYL and MACROMODEL

Treasurywala, A. M., Jaeger, E. P., Peterson, M. L.

Journal:

Journal of Computational Chemistry

Year:

1996

Language:

english

File:

PDF, 907 KB

english, 1996

30

Prediction of q -Values and Conformations of Gadolinium Chelates for Magnetic Resonance Imaging

Castonguay, L. A., Treasurywala, A. M., Caulfield, T. J., Jaeger, E. P., Kellar, K. E.

Journal:

Bioconjugate Chemistry

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

31

A model for compounds active against human rhinovirus-14 based on x-ray crystallography data

Diana, Guy D., Treasurywala, Adi M., Bailey, Thomas R., Oglesby, Richard C., Pevear, Daniel C., Dutko, Frank J.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.74 MB

english, 1990

32

ChemInform Abstract: TOTAL SYNTHESIS OF INDOLE AND DIHYDROINDOLE ALKALOIDS. IX. STUDIES ON THE SYNTHESIS OF BISINDOLE ALKALOIDS IN THE VINBLASTINE-VINCRISTINE SERIES. THE BIOGENETIC APPROACH

KUTNEY, J. P., HIBINO, T., JAHNGEN, E., OKUTANI, T., RATCLIFFE, A. H., TREASURYWALA, A. M., WUNDERLY, S.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 270 KB

1977

33

Conformational searching methods for small molecules. II. Genetic algorithm approach

R.S. Judson, E.P. Jaeger, A.M. Treasurywala, M.L. Peterson

Journal:

Journal of Computational Chemistry

Year:

1993

Language:

english

File:

PDF, 913 KB

english, 1993

34

The use of an algorithmic method for small molecule superimpositions in the design of antiviral agents

Guy Diana, Edward P. Jaeger, Melissa L. Peterson, Adi M. Treasurywala

Journal:

Journal of Computer-Aided Molecular Design

Year:

1993

Language:

english

File:

PDF, 607 KB

english, 1993

35

ChemInform Abstract: TOTAL SYNTHESIS OF INDOLE AND DIHYDROINDOLE ALKALOIDS PART 8, STUDIES ON THE SYNTHESIS OF BISINDOLE ALKALOIDS IN THE VINBLASTINE-VINCRISTINE SERIES, THE CLOROINDOLENINE APPROACH

KUTNEY, JAMES P., BECK, JOHN, BYLSMA, FEIKE, COOK, JAMES, CRETNEY, WALTER J., FUJI, KAORU, IMHOF, RENE, TREASURYWALA, ADI M.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 123 KB

1975

36

Validation of Screening Immobilized Peptide Libraries for Discovery of Protease Substrates

Singh, Jasbir, Allen, Martin P., Ator, Mark A., Gainor, James A., Whipple, David A., Solowiej, James E., Treasurywala, Adi M., Upson, Donald A.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1002 KB

english, 1995

37

Identification of transforming growth factor-β1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display

Sylvia A. Norman, Susan N. Rhodes, Sherri Treasurywala, Dominique B. Hoelzinger, Joan Rankin Shapiro, Adrienne C. Scheck

Journal:

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

38

Total Synthesis of Indole and Dihydroindole Alkaloids. VIII. Studies on the synthesis of bisindole alkaloids in the vinblastine-vincristine series. The chloroindolenine approach

James P. Kutney, John Beck, Feike Bylsma, James Cook, Walter J. Cretney, Kaoru Fuji, René Imhof, Adi M. Treasurywala

Journal:

Helvetica Chimica Acta

Year:

1975

Language:

english

File:

PDF, 2.55 MB

english, 1975

39

Novel Inhibitors of Potassium Ion Channels on Human T Lymphocytes

Michne, William F., Guiles, Joseph W., Treasurywala, Adi M., Castonguay, Laurie A., Weigelt, Carolyn A., Oconnor, Bernard, Volberg, Walter A., Grant, Alison M., Chadwick, Christopher C., Krafte, Dougl

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.88 MB

english, 1995

40

Antipicornavirus Compounds: Use of Rational Drug Design and Molecular Modelling

Diana, G. D., Nitz, T. J., Mallamo, J. P., Treasurywala, A.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

1993

Language:

english

File:

PDF, 493 KB

english, 1993

41

ChemInform Abstract: N-((5-(TRIFLUOROMETHYL)-6-METHOXY-1-NAPHTHALENYL)THIOXOMETHYL)-N-METHYLGLYCINE (TOLRESTAT), A POTENT, ORALLY ACTIVE ALDOSE REDUCTASE INHIBITOR

SESTANJ, K., BELLINI, F., FUNG, S., ABRAHAM, N., TREASURYWALA, A., HUMBER, L., SIMARD-DUQUESNE, N., DVORNIK, D.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 124 KB

1984

42

Determination of Pharmacophoric Geometry for Collagenase Inhibitors Using a Novel Computational Method and Its Verification Using Molecular Dynamics, NMR, and X-ray Crystallography

Ghose, Arup K., Logan, Margaret E., Treasurywala, Adi M., Wang, Hsin, Wahl, Robert C., Tomczuk, Bruce E., Gowravaram, Madhusudhan R., Jaeger, Edward P., Wendoloski, John J.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 2.64 MB

english, 1995

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